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NexGard (afoxolaner) Chewables
  • NexGard (afoxolaner) Chewables
  • NexGard (afoxolaner) Chewables

NexGard (afoxolaner) Chewables

  • From the makers of FRONTLINE Plus, the #1 choice of veterinarians
  • It is the first flea and tick killer in a beef-falavored chew
  • Tasty chewable approved to kill both fleas and ticks.
  • It kills adult fleas before they lay eggs. 
  • NEXGARD is available in four sizes of beef-flavored soft chewables
  • Each chewable size is available in color-coded packages of 3 or 6 beef-flavored chewables.

From $35.95






Product Detail: NexGard (afoxolaner) Chewables


NexGard (afoxolaner) is FDA-approved for veterinarian use and demonstrated 100% effectiveness against adult fleas 24 hours post-infestation for 35 days. NexGard rapidly kills adult fleas and is indicated for the treatment and prevention of flea (Ctenocephalides spp.) infestations, for the control of newly acquired adult fleas, and for the control of Flea Allergy Dermatitis (FAD). Following administration, fleas are killed within 6-8 hours. Rapid onset of action kills newly acquired fleas before they can lay eggs.


How NexGard works

Effective flea control with NexGard prevents flea tapeworm infestation in dogs. Nexgard treats and controls Paralysis ticks (Ixodes holocyclus), Brown Dog ticks (Rhipicephalus sanguineus), treatment and control of American Dog tick (Dermacentor variabilis), and Bush ticks (Haemaphysalis longicornis) for one month. NexGard provides effective control of pre-existing Paralysis tick infestations within 24 hours. Ixodes holocyclus ticks do not occur in Western Australia. 

NexGard treats and controls demodectic mange caused by Demodex spp., sarcoptic mange caused by Sarcoptes scabiei, and ear mite (Otodectes cynotis) infestations.


What is the active ingredient of NexGard?

Active ingredient:


How can NexGard be administered to dogs?

NexGard is a soft, highly palatable chewable and is readily consumed by dogs when offered as a treat. Alternatively, NexGard may be added intact to a small amount of dog food. Care should be taken that the dog consumes the complete dose, and treated dogs should be observed for a few minutes to ensure that part of the dose is not lost or rejected. If it is suspected that any of the dose has been lost, treat again with another full dose.

The recommended dosage is 2.5 mg per kg bodyweight:


Dog Weight (kg)    Chewable size (g)    Afoxolaner (mg/chew)    

2-4                                        0.5                              11.3

4.1-10                                   1.25                            28.3

10.1-25                                 3                                 68.0

25.1-50                                 6                                 136.0

For dogs over 50 kg, administer the appropriate combination of chewables.

For optimal performance, treat your dog on or about the same day each month.


Is NexGard safe for dogs?

NexGard was shown to be safe in various breeds of dogs and in puppies 8 weeks and older. NexGard may be administered in conjunction with gastrointestinal worm or heartworm treatments administered according to label directions. Afoxolaner is part of the isoxazoline family of chemicals. Adverse reactions to this family of chemicals are rarely observed but may include vomiting, diarrhoea, lethargy, inappetance, itching, and very rarely, seizures. Most adverse reactions are self-limiting and of short duration. If you have any concerns, please speak to your veterinarian.


Ratings & Reviews

Based on 98 Review(s)

Average Rating


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Most Recent Reviews

Nexgard is the best
Written by Debi
Sep 18, 2018

I used several different products to control flea's from my pet's and home. Then I tried Nexgard it works really great. I never have a flea issue anymore. Thank you for offering it for such an incredible price. Much more affordable than from my vet's office. Thank's again !!!
Written by Sue
Aug 22, 2018

Llove this product, always got it from my vet at a much higher price. So happy a friend referred me to you all. Thanks for handling top products at a very reasonable price :)

Nexgard Kills Ticks
Written by MayBaby32
Aug 22, 2018

We moved to Maine, which is basically tick heaven. Since being on this medication, my dog, Digby, has not brought one live tick into the house. (I wish the same could be said for me!) And buying it from Joe?s saves us a bundle too.

Written by Bjazzy
Aug 01, 2018

As soon as my puppy reached the minimum weight, we have her Nex Guard, because the veterinarian recommended it. My puppy loves it, gobbled it right down! No messy oils down her back, no struggling to get a pill down her throat! No fleas, or anything else.

NexGard Review
Written by Teresa Flihan
Jul 04, 2018

Since giving NexGard to our two dogs they haven't had fleas or ticks. Previously they have had ticks occasionally. We're all very satisfied!!!

Works Great
Written by Red Barn
May 29, 2018

When I find a tick on my 75 lb. dog, it is always dead.

Awesome meds
Written by jennie hanner
May 22, 2018

This product is the best and so is Joe's Petmeds. I wouldn't shop anywhere else. Joe's Petmeds makes it so easy to get everything you need right from home. NexGard keeps my dogs free from fleas and ticks and they love the meat flavored chews.

Written by sherrie york
May 08, 2018

Really works well on my fur babies ,easy to give (chewable)yea!!

So much easier than pills or drops!
Written by Nancy B
May 06, 2018

Worth every penny! Better control than drops on the skin that didn?t always protect my big outside dog. So much easier to give than the pills, which he would spit out and I?d have to force feed. He chews this right up and licks his chops after! Haven?t seen a flea or tick on him ever!

Best Flea Control
Written by Regina
Feb 17, 2018

We took in a stray dog that was covered in fleas. We started using Nexgard to control them, and it's the best flea control PERIOD! We tried collars and topical stuff, but nothing seemed to work. Hands down best product. Joe's Pet Meds also has the BEST price for Nexgard. I will continue to shop here in the future!