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Heartgard Plus Chewables
  • Heartgard Plus Chewables

Heartgard Plus Chewables

  • Highly effective dewomer that eliminates the tissue stages of heartworm larvae and removes adult roundworms and hookworms from dogs.
  • Made with real beef and is a chewy treat for dogs.
  • Easy to administer.



From $34.95





Style Number: MSD24-CONFIG

Product Detail: Heartgard Plus Chewables

Heartgard Plus

Heartgard Plus is indicated for use in dogs to prevent canine heartworm disease by eliminating the tissue stage of heartworm larvae for a month (30 days) after infection, and for the treatment and control of roundworms and hookworms.


What are the active ingredients in Heartgard Plus?

Active ingredients: 


How Heartgard Plus works

Heartgard Plus prevents canine heartworm disease by eliminating the tissue stage of heartworm larvae (Dirofilaria immitis) for a month (30 days) after infection and for the treatment and control of ascarids (Toxocara canisToxascaris leonina) and hookworms (Ancylostoma caninumUncinaria stenocephalaAncylostoma braziliense).


How can you properly administer Heartgard Plus?

Heartgard Plus (ivermectin/pyrantel) should be administered orally at monthly intervals at the recommended minimum dose level of 6 mcg of ivermectin per kilogram (2.72 mcg/lb) and 5 mg of pyrantel (as pamoate salt) per kg (2.27 mg/lb) of body weight. The recommended dosing schedule for the prevention of canine heartworm disease and for the treatment and control of ascarids and hookworms is as follows:

Dog Weight    Chewables per month    Ivermectin    Pyrantel    Color coding

Up to 25 lbs                        1                         68 mcg         57 mcg           Blue

26 to 50 lbs                        1                         136 mcg       114 mcg          Green

51 to 100 lbs                      1                         272 mcg       228 mcg          Brown

Heartgard Plus is recommended for dogs 6 weeks of age and older. For dogs over 100 lb use the appropriate combination of these chewables.


What are the precautions in using Heartgard Plus?

All dogs should be tested for existing heartworm infection before starting treatment with Heartgard Plus which is not effective against adult D. immitis. Infected dogs must be treated to remove adult heartworms and microfilariae before initiating a program with Heartgard Plus. While some microfilariae may be killed by the ivermectin in Heartgard Plus at the recommended dose level, Heartgard Plus is not effective for microfilariae clearance. A mild hypersensitivity-type reaction, presumably due to dead or dying microfilariae and particularly involving a transient diarrhea, has been observed in clinical trials with ivermectin alone after treatment of some dogs that have circulating microfilariae.


Ratings & Reviews

Based on 222 Review(s)

Average Rating


Ratings Overview











Most Recent Reviews

Heartgard Plus Chewables
Written by Chi chi
Sep 15, 2015

Chichi loves this chewables. It's a little bit pricey compare to other meds but I assure you this one is the best. And my dogs only deserve the best. Not only the product is effective, the dogs love it too. is wonderful
Written by Kimberly Hicks
Sep 11, 2015

I have been a new mommy to a wonderful dog that I named Emma for about a year and six months now. This is also how long that I have been ordering her Heartguard plus medications from I am very happy to report that my babies first hearworm test was negative for heartworms. I am very thankful for Without their sight I would not be able to afford her medications. Thank you for the huge discounts. Thank you for making your medications so affordable so I can take care of my baby. Emma says, "ruff-ruff" Thankyou.

Best preventives
Written by Julius
Sep 10, 2015

Best heart worm preventive. I live in Florida and parasites here are everywhere. Good thing I get to give my dog a heart worm preventive monthly. This is a big help. I don't want my dogs to catch heart worms. And Heartgard Chewables are helping me through it. Thanks.

Best heart worm preventive
Written by Jewel
Sep 08, 2015

So far, this is the best heart worm preventive I've ever tried to my dog. No heart worms ever since I gave them this. And the dogs totally love it. They love the taste they're even asking for more.

Heartgard Plus
Written by CJ
Sep 07, 2015

My 'fussy' SkipperKee loves it - never refuses it. Service is awesome - have ordered several times from Joes - prices are fair and receive product promptly.

Protection for Duke & Tracey
Written by Joan Mills
Sep 05, 2015

I love the heartgard chewables that I get from Joes for my dogs Tracey & Duke,it is so easy to get them to take them and I know they are protected against Heart worms.

Great product
Written by lilbonfire
Sep 05, 2015

We have been using heartgard plus for our dogs for 5 years now and we have never had any issues. It not only protects them, but they love the taste so much they think they are getting a treat!

great product
Written by bonnie tewksbury
Sep 04, 2015

i love this it works great for my dogs and its so easy to give to them

Heartgard plus
Written by Vi Margly
Sep 04, 2015

I have been buying tis product for the past several years ad my dogs consider it their once a month treat and they test negative for heart worms each year. Delivery from Joes is always timely and the packaging secures the product. Not to mention the price is good.

Written by Labcur
Sep 04, 2015

Heartguard plus is the best and Joes has the best prices! My dogs will not take any of the other type heartworm pills, only the chewables, so these are great! I always receive them quick when i order also!