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Heartgard Plus Chewables
  • Heartgard Plus Chewables

Heartgard Plus Chewables

  • Highly effective dewomer that eliminates the tissue stages of heartworm larvae and removes adult roundworms and hookworms from dogs.
  • Made with real beef and is a chewy treat for dogs.
  • Easy to administer.



From $34.95





Style Number: MSD24-CONFIG

Product Detail: Heartgard Plus Chewables

Heartgard Plus

Heartgard Plus is indicated for use in dogs to prevent canine heartworm disease by eliminating the tissue stage of heartworm larvae for a month (30 days) after infection, and for the treatment and control of roundworms and hookworms.


What are the active ingredients in Heartgard Plus?

Active ingredients: 


How Heartgard Plus works

Heartgard Plus prevents canine heartworm disease by eliminating the tissue stage of heartworm larvae (Dirofilaria immitis) for a month (30 days) after infection and for the treatment and control of ascarids (Toxocara canisToxascaris leonina) and hookworms (Ancylostoma caninumUncinaria stenocephalaAncylostoma braziliense).


How can you properly administer Heartgard Plus?

Heartgard Plus (ivermectin/pyrantel) should be administered orally at monthly intervals at the recommended minimum dose level of 6 mcg of ivermectin per kilogram (2.72 mcg/lb) and 5 mg of pyrantel (as pamoate salt) per kg (2.27 mg/lb) of body weight. The recommended dosing schedule for the prevention of canine heartworm disease and for the treatment and control of ascarids and hookworms is as follows:

Dog Weight    Chewables per month    Ivermectin    Pyrantel    Color coding

Up to 25 lbs                        1                         68 mcg         57 mcg           Blue

26 to 50 lbs                        1                         136 mcg       114 mcg          Green

51 to 100 lbs                      1                         272 mcg       228 mcg          Brown

Heartgard Plus is recommended for dogs 6 weeks of age and older. For dogs over 100 lb use the appropriate combination of these chewables.


What are the precautions in using Heartgard Plus?

All dogs should be tested for existing heartworm infection before starting treatment with Heartgard Plus which is not effective against adult D. immitis. Infected dogs must be treated to remove adult heartworms and microfilariae before initiating a program with Heartgard Plus. While some microfilariae may be killed by the ivermectin in Heartgard Plus at the recommended dose level, Heartgard Plus is not effective for microfilariae clearance. A mild hypersensitivity-type reaction, presumably due to dead or dying microfilariae and particularly involving a transient diarrhea, has been observed in clinical trials with ivermectin alone after treatment of some dogs that have circulating microfilariae.


Ratings & Reviews

Based on 222 Review(s)

Average Rating


Ratings Overview











Most Recent Reviews

Written by Chris
Jun 03, 2017

Friend of our recommended Joes and we have ordered Heartgaurd from Joes before and we were very satisfied.

Written by Sharron's Pet Sitting
Apr 26, 2017

As an owner of a rescued dog with heartwoms that is now heartworm free, I use this product.

heartworm prevention
Written by gidgit detwiler
Mar 23, 2017

I have been purchasing heartgard from this site for years. it is inexpensive, and we get it quickly. I will continue to shop at this web site and I recommend it to friends and family

Written by Lorry
Mar 23, 2017

I have used Heartgard for years and will continue to do so. Yes, I know there is a generic but have not gotten the courage to try it yet. Heartworms can kill a dog and so I continue to buy the original -- it works without upset to my pets.

Heartgard Plus Chewables
Written by Bobby Hughes
Mar 14, 2017

I have been ordering this heartworm medicine from Joe's Pet Meds for over a year now, and I always have had satisfactory results, so far. If things continue this well, I will continued ordering the same meds from the same company. Thanks for helping me take care of my little dog. I have also recommended this source to some friends. I'm not sure whether or not they have followed my advice though.

Heartguard for any size
Written by Harvey
Mar 12, 2017

I buy small, medium and large dog Heartguard - we have every kind and size! I have been buying from Joe's Pet Meds for years for the best prices - our household is Heartworm Free!

Written by John Thompson
Mar 09, 2017

We have used HeartGard for our shelties since 1997 and have never had any problems related to heartworms. Our dogs look forward to their monthly soft chew treat every time we pull out the package! The protection HeartGard offers our gang keeps us trusting their product and keeps us coming back to buy it again every time we run out! We strongly recommend HeartGard to all our puppy buyers for a life long protection from heart worms.

Written by Acosner
Feb 22, 2017

We have been buying from Joe's Petmeds for over a year now and are completely happy with all products we have purchased.

Very Pleased.
Written by Sophie
Feb 12, 2017

We have been purchasing HeartGard Plus for several years now. We have had great results with this product for our little dogs. They like the taste so they will take them without fuss. The price is also reasonable. Thank you Joe's for offering this product for our dogs.

Written by Joshua Zech
Feb 04, 2017

Works well, great for the dog. Great price at Joes!