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Heartgard Plus Chewables
  • Heartgard Plus Chewables

Heartgard Plus Chewables

  • Highly effective dewomer that eliminates the tissue stages of heartworm larvae and removes adult roundworms and hookworms from dogs.
  • Made with real beef and is a chewy treat for dogs.
  • Easy to administer.



From $34.95





Style Number: MSD24-CONFIG

Product Detail: Heartgard Plus Chewables

Heartgard Plus

Heartgard Plus is indicated for use in dogs to prevent canine heartworm disease by eliminating the tissue stage of heartworm larvae for a month (30 days) after infection, and for the treatment and control of roundworms and hookworms.


What are the active ingredients in Heartgard Plus?

Active ingredients: 


How Heartgard Plus works

Heartgard Plus prevents canine heartworm disease by eliminating the tissue stage of heartworm larvae (Dirofilaria immitis) for a month (30 days) after infection and for the treatment and control of ascarids (Toxocara canisToxascaris leonina) and hookworms (Ancylostoma caninumUncinaria stenocephalaAncylostoma braziliense).


How can you properly administer Heartgard Plus?

Heartgard Plus (ivermectin/pyrantel) should be administered orally at monthly intervals at the recommended minimum dose level of 6 mcg of ivermectin per kilogram (2.72 mcg/lb) and 5 mg of pyrantel (as pamoate salt) per kg (2.27 mg/lb) of body weight. The recommended dosing schedule for the prevention of canine heartworm disease and for the treatment and control of ascarids and hookworms is as follows:

Dog Weight    Chewables per month    Ivermectin    Pyrantel    Color coding

Up to 25 lbs                        1                         68 mcg         57 mcg           Blue

26 to 50 lbs                        1                         136 mcg       114 mcg          Green

51 to 100 lbs                      1                         272 mcg       228 mcg          Brown

Heartgard Plus is recommended for dogs 6 weeks of age and older. For dogs over 100 lb use the appropriate combination of these chewables.


What are the precautions in using Heartgard Plus?

All dogs should be tested for existing heartworm infection before starting treatment with Heartgard Plus which is not effective against adult D. immitis. Infected dogs must be treated to remove adult heartworms and microfilariae before initiating a program with Heartgard Plus. While some microfilariae may be killed by the ivermectin in Heartgard Plus at the recommended dose level, Heartgard Plus is not effective for microfilariae clearance. A mild hypersensitivity-type reaction, presumably due to dead or dying microfilariae and particularly involving a transient diarrhea, has been observed in clinical trials with ivermectin alone after treatment of some dogs that have circulating microfilariae.


Ratings & Reviews

Based on 222 Review(s)

Average Rating


Ratings Overview











Most Recent Reviews

Heartgard Plus + Saving
Written by Megan
Jan 03, 2015

I've been buying from Joe's Pet Meds for years and have recommended Joe's to several people due to the great price and service. I know some people have some concerns about this being a Non-US branded product. I have never had a single problem with the quality or packaging of this AUTHENTIC product. As a friend once put it: if it's good enough to fight the critters in Australia- where they have A LOT of stuff that will kill you and your pet- it's good enough for the US! Don't buy into the hype about how a product not branded for the US market is inferior! This works just as well, I don't have to send a Rx from my vet (yes, he's regularly tested), and I save money! It's a win/win for me and my doggie!!

HeartGard Plus
Written by N.Cynor
Jan 02, 2015

We have bought from Joe's Pet Meds for many years now. We have always had great service and best prices around. My vet doesn't like the fact we get it for such a reasonable price, but now a days you have to watch every penny! Thanks Joe's!

Completely Satisfied
Written by Midwest Patron
Dec 18, 2014

I have used this product for 6 years, and my 10-year old dog has been ringworm free... its great price doesn't hurt either :)

Heartguard Plus for big and small
Written by Harvey
Dec 15, 2014

I have bought Heartguard Plus for my under 25 and 50-100 lb dogs from Joe's Pet Meds for years. You can't beat the price. Well below vet prices.

Great Company
Written by Ryan
Dec 09, 2014

Easily the cheapest pet meds you can buy online.

So happy
Written by ajb1944
Dec 02, 2014

We're so happy with Joe's pet meds. We don't know what we would do without them. We have 4 dogs now. (2 rescues) and it's just not doable to pay the USA prices. So Joe's Pet meds is our angel to the rescue.

Love the Price
Written by Linda
Nov 29, 2014

I've been using Joe's Pet Meds to order our dog's Heartworm medication for about 6 years now. No problem with our dog....just our vet. She wants us to buy from her. But we insist on being smart and that means being frugal. Sadie thinks she is getting a yummy treat and we know we have a healthy dog.Thank you Joe's Pet Meds for quality meds for our dog and great prices!
Written by Michelle D.
Nov 27, 2014

My dog loves getting these. They are like a reward for him, which makes giving him his medication a great experience. He has never had heart worms so they must be working!

Written by roxanne
Nov 13, 2014

I've been ordering from for over a year or so now, and they ship super fast, no hassles and always have the best prices around. My animals get the heart worm protection they need and I don't have to pay the hefty overpriced vets, nor have to deal with getting a prescription which they always give you problems because they want you to purchase from them. Thanks Joes ! you make things smooth and easy. Keep up the good work and awesome customer service.

I Don't Have To FORCE My Dogs To Eat It!
Written by Rachel R
Nov 05, 2014

This is the one and only medication, I don't have to physically force down my two Jack Russell's throats. They actually like it! Thanks.