Joes Pet Meds Store Review Banner

Joe's Pet Meds
Ratings & Reviews

Care To Give Us A Feedback?

Write a review here and let the world know what you think about our service, prices, product range or shipping.

If you would like to review a specific product then please search for the product you would like to review and place your review on that page instead.

Joes Pet Meds Store Review Banner

Frontline Plus

Frontline Plus features

  • Kills fleas for at least one month
  • Controls and treats Flea Allergy Dermatitis
  • Kills all known ticks for at least one month
  • Water-resistant
  • Easy to administer spot-on application
  • Each tube contains Fipronil & S-Methoprene



From $38.95





Style Number: MSD14-CONFIG

Product Detail: Frontline Plus

Information about Frontline Plus

Frontline Plus provides protection against fleas and ticks, and contains a special ingredient to kill flea eggs and larvae. By stopping the development of new fleas, Frontline Plus provides the most complete flea and tick protection available. Frontline Plus kills 100% of fleas and ticks within 48 hours, including many ticks that transmit dangerous diseases that can affect other pets and humans.

Frontline Plus Flea Control has been formulated for use on puppies and kittens from eight weeks of age and is safe for use on pregnant and lactating animals. It is a water-resistant flea medication, so it continues to kill fleas even after shampooing, swimming, rain or exposure to sunlight.

Product Information Schedule

N.B. Pet Shed sells the Australian versions of the products listed below.
Metric conversion: 1 kg = 2.2 lbs

  Dosage Active Ingredients For cats
Frontline Plus for Cats (Green Box)      
Australian Version, NRA Approval No. 54524 0.5 mL 100 g/L Fipronil & 120 g/L (S)-Methoprene 8 weeks or older
USA Version, EPA Reg. No. 65331-4 0.017 fl oz (0.5 ml) 9.8% Fipronil & 11.8% (S)-Methoprene (by weight) 8 weeks or older
  Dosage Concentration For dogs weighing
Frontline Plus for Dogs (Orange Box)      
Australian Version, NRA Approval No. 54523 0.67 mL 100 g/L Fipronil & 90 g/L (S)-Methoprene Up to 10kg
USA Version, EPA Reg. No. 65331-5 0.023 fl oz (0.67 mL) 9.8% Fipronil & 8.8% (S)-Methoprene (by weight) Up to 22 lbs
Frontline Plus for Dogs (Blue Box)      
Australian Version, NRA Approval No. 54523 1.34 mL 100 g/L Fipronil & 90 g/L (S)-Methoprene 10-20 kg
USA Version, EPA Reg. No. 65331-5 0.045 fl oz (1.34 mL) 9.8% Fipronil & 8.8% (S)-Methoprene (by weight) 23-44 lbs
Frontline Plus for Dogs (Purple Box)      
Australian Version, NRA Approval No. 54523 2.68 mL 100 g/L Fipronil & 90 g/L (S)-Methoprene 20-40 kg
USA Version, EPA Reg. No. 65331-5 0.091 fl oz (2.68 mL) 9.8% Fipronil & 8.8% (S)-Methoprene (by weight) 45-88 lbs
Frontline Plus for Dogs (Red Box)      
Australian Version, NRA Approval No. 54523 4.02 mL 100 g/L Fipronil & 90 g/L (S)-Methoprene 40-60 kg
USA Version, EPA Reg. No. 65331-5 0.136 fl oz (4.02 mL) 9.8% Fipronil & 8.8% (S)-Methoprene (by weight) 89-132 lbs

Frontline Plus has been approved for sale in Australia by the APVMA. The US equivalent of this product has been approved for sale by the EPA.

Both the Australian and US products contain the same active ingredients, Fipronil & (S)-Methoprene.

However, the products sold by Pet Shed are sold in Australian packaging which has not been approved for sale in the US. As a consequence, the Australian packaging does not have EPA approval and the sale and purchase of products in the Australian packaging may be illegal in the US.

If swallowed call a poison control center or doctor immediately for treatment advice. For hazards to domestic animals the 24 hour assistance line within the U.S.A. is 1-800-660-1842.

The Product Information Schedule above indicates some of the material differences between the Australian and U.S.A. versions.

Ratings & Reviews

Based on 148 Review(s)

Average Rating


Ratings Overview











Most Recent Reviews

Best thing i can use for the Money
Written by Tammy
Apr 01, 2017

No issues and my dog is allergic to other flea meds . Also great for cats Do not use the dog For your cats

Would recommend Frontline Plus
Written by Lisa from Ohio
Mar 31, 2017

I have been using this product for several years now and have had no problems, as far as I'm concerned it works great and I would recommend it. I would also like to mention, last yr. when I placed my order for a 12 pk, after 3 weeks(15 working days) it still had not arrived. I contacted customer service and they immediately send out a second order. Both orders then showed up within 3 days of each other. After contacting customer service again to let them know, they gave me the option of keeping the second order and paying for it or returning it. I opted to return it. 5 stars for customer service. Thank you.

No fleas or ticks! Best prices.
Written by Marilyn
Jan 04, 2017

We have been using Frontline Plus for several years. My brother told me about joespetmeds. He had researched prices and told me they had the best ! He was right. Doing research myself to be sure. Joe's is the best! Never a problem with delivery. And the best thing no fleas or ticks! We live in the country and have a Shepherd and a cat. The dog is outside during the day and loves to walk with us in the woods . We've had ticks on us, ugh! But never any embedded on our dog . The cat likes to go outside and no sign of fleas or ticks. A great product.
Written by Debra Owens
Nov 27, 2016

I have just replaced my order for the dog & cat Front line+ Generic products. I always use to use regular frontline but it has become so expensive. I have switched to the generic and see no difference. I despise fleas in my home, and being able to afford this from Joe's Pets is a godsend for me. I am able to purchase a few treats as well to put under the christmas tree with my savings. I would not mind winning some toys either!! Hint Hint. Anyway I love this site and thank you for all you do! Debra Owens

frontline plus
Written by Barbara McKinney
Oct 12, 2016

I have two toy breeds, and have used Frontline plus for five years. In Virginia there is never a kill season for fleas.My dogs are house dogs except for the bark that means ( let me out so I can come back in and get a treat) This happens quite often. In the years we have used Frontline have never seen one flea. we also have two cats in the household with no fleas. I am a happy happy customer..

Fleas will flee!
Written by Evan
Oct 09, 2016

I've always been happy with the original Frontline Plus for cats. It's very easy to apply and lasts long enough for my kitties to be happy. I love the Plus because it's of the few applications that also takes care of Ticks too!

Great product and excellent service
Written by George Otero
Aug 20, 2016

This a great site to purchase your pet medical supplies. Great price and quick delivery to the United States

Great Price!!
Written by ChristinaW
Aug 13, 2016

Best price I have found for this product! Frontline works like a charm!

Written by Tara91c08
Jul 18, 2016

Always the cheapest by at least $10.00!

2 thumbs up!
Written by Kristin O.
Jul 06, 2016

I was amazed by the price of the heartworm preventative I purchased. The prices are amazing and delivery was fast. I will continue to shop here for my pets needs!