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Generic Sentinel Flavor Tabs (Milbemycin oxime & Lufenuron)

  • Preventer Plus Flavor Tabs are given just once a month to prevent heartworm disease and flea populations in dogs and puppies.
  • Controls flea populations and adult hookworms .
  • Removes and controls adult roundworm and whipworm infection in dogs and puppies.

From $21.95






Product Detail: Generic Sentinel Flavor Tabs (Milbemycin oxime & Lufenuron)

Preventer Plus Flavor Tabs

Preventer Plus Flavor Tabs (milbemycin oxime + lufenuron) are available in four tablet sizes in color-coded packages for oral administration to dogs and puppies according to their weight. Each tablet is formulated to provide a minimum of 0.23 mg/lb (0.5 mg/kg) body weight of milbemycin oxime and 4.55 mg/pound (10 mg/kg) body weight of lufenuron. Milbemycin oxime consists of the oxime derivatives of 5-didehydromilbemycins in the ratio of approximately 80% A4 and 20% A3 Milbemycin oxime is classified as a macrocyclic antihelminthic.

Lufenuron is a benozylphenylurea derivative and classified as an insect develpoment inhibitor.


IndicationsPreventer Plus Flavor Tabs are indicated for use in dogs and puppies, four weeks of age and older, and two pounds body weight or greater. Preventer Plus Flavor Tabs are indicated for the prevention of heartworm disease caused by Dirofilaria immitis, for the prevention and control of flea populations, the control of adult Ancylostoma caninum (hookworm), and the removal and control of adult Toxocara canis and Toxascaris leonina (roundworms) and Trichuris vulpis (whipworm) infections.

Lufenuron controls flea populations by preveting the development of flea eggs and does not kill adult fleas. Concurrent use of adulticide product may be necessary for adequate control of adult fleas.

DosagePreventer Plus Flavor Tabs are given orally, once a month, at the recommended minimum dosage rate of 0.23 mg/lb (0.5mg/kg) milbemycin oxime and 4.55 mg/lb (10 mg/kg) lufenuron.

Dogs over 100 lbs are provided the appropriate combination of tablets.

AdministrationTo ensure adequate absorption, always administer Preventer Plus Flavor Tabs to dogs immediately after or in conjunction with a normal meal.

Recommended Dosage Schedule for Dogs
Dog Weight         Milbemycin Oxime Per Tablet       Lufenuron Per Tablet                       
2-10 lbs.                            2.3 mg                                        46.0 mg
11-25 lbs.                          5.75 mg                                      115 mg
26-50 lbs.                         11.5 mg                                       230mg
51-100 lbs.                       23.0 mg                                       460 mg

Preventer Plus Flavor Tabs are palatable and most dogs will consume the tablet when offered by the owner. As an alternative to direct dosing, the tablets can be hidden in food. Be certain the dog consumes the entire tablet. Administer Preventer Plus Flavor Tabs to dogs immediately after or in conjunction with a normal meal. Food is essential for adequate absorption of lufenuron. Watch the dog closely following administration to be sure the entire dose have been consumed

Preventer Plus Flavor Tabs must be administered monthly, preferably on the same date each month. Treatment may begin at any time of year. In geographic areas where mosquitoes and fleas are seasonal, the treatment schedule should begin one month prior to the expected onset and should continue until the end of mosquito and flea season. In areas with year-round infestations, treatment should continue through the entire year without interruption.

If a dose is missed and a 30-day interval between dosing is exceeded, administer Preventer Plus immediately and resume the monthly dosing schedule. If Preventer Plus Flavor Tabs replace daily diethylcarbamazine (DEC) for heartworm prevention, the first dose must be given within 30 days after the last dose of DEC.

PrecautionsDo not use in puppies less than four weeks of age and less than two pounds of body weight. Prior to initiation of the Preventer Plus Flavor Tabs treatment program, dogs should be tested for existing heartworm infections. Infected dogs should be treated to remove adult heartworms and microfilariae prior to initiating treatment with Preventer Plus Flavor Tabs. Mild transient hypersensitivity reactions manifested as labored respiration, vomiting, salivation and lethargy, have been noted in some treated dogs carrying a high number of circulating microfilariae. These reactions are presumably caused by release of protein from dead or dying microfilariae.

Preventer Plus Flavor Tabs immediately break the flea life cycle by inhibiting egg development. However, pre-existing flea populations may continue to develop and emerge after treatment has begun. Based on results of clinical studies, this emergence generally occurs during the first 30-60 days. Therefore, noticeable control may not be observed until several weeks after dosing when a pre-existing infestation is present.

If a Preventer Plus- treated dog comes in contact with a flea-infested environment, adult fleas may infest the treated animal. These adult fleas are unable to produce a viable offspring. The temporary use of an adulticide product may be necessary to kill these adult fleas.

Storage Conditions: Store in a dry place at controlled room temperature between 59° and 77°F (15-25°C).


Ratings & Reviews

Based on 8 Review(s)

Average Rating


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Most Recent Reviews

Written by Sassy
Apr 14, 2021

Great price using for years

Sentinel generic
Written by Patricia
Jul 14, 2019

Thank you for this great price. I work with a lot of low income elderly clients who can't afford dog meds. Fleas are such a huge problem in Florida.Vet visits are expensive and this product is a huge help for them and myself. Thank you!!

So Glad I Found This Product
Written by Ann
Jul 04, 2019

I am so glad I found this product. I have used it on all sizes of dogs from 3 lb Chihuahuas to over a hundred lbs ( on the Vet's scales) Rottweilers. They have all responded well and have shown no signs of any ill effects. It is easy to use and saves me time and money. Thanks Joe's Pet Meds.

Heart Worm Prevention
Written by Lwelchdog
Jun 20, 2019

I have been buying Preventor for years. I keep all my dogs on it all the time, 12 months of the year. I live in an area where it can get up to 70 degrees F in January or 20 degrees in January. We never know, I have seen mosquitoes in January and February so I take no chances and keep Preventor in the house all the time.

Preventer Plus
Written by Jackie
Apr 06, 2019

I have ordered this product in the past as well as my new order. I use this on my Labrador Retrievers and have not had any side affects. All ingredients are the same as the Sentinel. Can't go wrong with this price !

Great product and great place!
Written by Robin
Sep 26, 2018

I have been ordering and using this flea/heartworm control for about 3 years and I have found it to be the best on the market even though it is the generic form. When we moved to Florida from Arizona we had been using Frontline for flea control. For over a year we still battled fleas and I tried every other brand that I could afford, then I found Joe's Pet Meds and Preventer Plus. With the first use the fleas disappeared within 2 days! So I was convinced that this product was best and the price is outstanding! I have been using it and Joe's Pet meds since! Thank you Joe's Pet meds and Preventer Plus!

great product
Written by scarlet mayes
Jan 24, 2018

great product, great price

Love it!
Written by Chantail
Oct 11, 2017

I had ordered this at the start of spring and let me tell you, I didn't see one flea this year! Its a great product. To have flea control and worm control including heart worm in one product is the best way to go. I saw no side effects in either of my dogs.